欧文原著

1.
Kanasaki H, Oride A, Mitsuo T, Miyazaki K: Occurrence of pre- and postoperative stress urinary incontinence in 105 patients who underwent tension-free vaginal mesh surgery for pelvic organ prolapse: A retrospective study.
ISRN Obstet Gynecol 2012: published online, 2014

2.
Oride A, Kanasaki H, Mijiddorj T, Sukhbaatar U, Miyazaki K: Trichostatin A specifically stimulates gonadotropin FSHβ gene expression in gonadotroph LβT2 cells.
Endocrine J 61:335-342, 2014

3.
Sukhbaatar U, Kanasaki H, Mijiddorj T, Oride A, Miyazaki K: Expression of gonadotropin-inhibitory hormone receptors in mouse pituitary gonadotroph LβT2 cells and hypothalamic gonadotropin-releasing hormone-producing GT1-7 cells.
Endocr J 61, 25-34, 2014

4.
Sukhbaatar U, Kanasaki H, Mijiddorj T, Oride A, Miyazaki K: Kisspeptin induces expression of gonadotropin-releasing hormone receptor in GnRH-producing GT1-7 cells overexpressing G protein-coupled receptor 54.
Gen Comp Endocrinol 194: 94-101, 2013

5.
Kanasaki H, Mijiddorj T, Sukhbaatar U, Oride A, Miyazaki K: Pituitary adenylate cyclase-activating polypeptide (PACAP) increases expression of the gonadotropin-releasing hormone (GnRH) receptor in GnRH-producing GT1-7 cells overexpressiong PACAP type I receptor.
Gen Comp Endocrinol 193: 95-102, 2013

6.
Kanasaki H, Purwana IN, Aki Oride, Mijiddorj, U. Sukhbaatar, Miyazaki K:
Circulating kisspeptin and pituitary adenylate cyclase-activating polypeptide (PACAP) do not correlate with gonadotropins serum levels.
Gynecol Endocrinol 29: 583-587, 2013

7.
Oride A, Kanasaki H, Miyazaki K: Therapeutic process of gynecological pelvic abscess-Retrospective review of 20 Cases.
Surg Sci 4: 202-209, 2013

8.
Mijiddorj T, Kanasaki H, Unurjargal S, Oride A, Purwana IN, and Miyazaki K: Prolonged stimulation with thyrotropin-releasing hormone and pituitary adenylate cyclase-activating polypeptide desensitize their receptor functions in prolactin-producing GH3 cells.
Mol Cell Endocrinol 365: 139-145, 2013

9.
Kanasaki H, Oride A, Miyazaki K: Laparoscopic surgery in elderly patients aged 65 years and older with gynecologic disease.
ISRN Obstet Gynecol 2012: published online, 2012

10.
Kanasaki H, Purwana IN, Mijiddorj T, Sukhbaatar U, Oride A, Miyazaki K: Effects of estradiol and progesterone on gonadotropin LHβ- and FSHβ-subunit promoter activities in gonadotroph LβT2 cells.
Neuro Endocrinol Lett 33: 608-613, 2012

11.
Kanasaki H, Oride A, Miyazaki K: Popularization of tension-free vaginal mesh surgery for the treatment of pelvic organ prolapse in Japan: A retrospective review of the first 50 procedures performed by a gynecologist.
Int J Surg 10: 578-580, 2012

12.
Mijiddorj T, Kanasaki H, Purwana IN, Oride A, Sukhbaatar U and Miyazaki K: Effects of estradiol and progesterone on prolactin transcriptional activity in somatolactotrophic cells.
Endocr J 59: 867-879, 2012

13.
Mijiddorj T, Kanasaki H, Purwana IN, Oride A, Sukhbaatar U and Miyazaki K: Role of neurokinin B and dynorphin A in pituitary gonadotroph and somatolactotroph cell lines.
Endocr J 59: 631-640, 2012

14.
Kanasaki H, Oride A, Nakayama K, Miyazaki K: Evaluation of Immediate Laparoscopic surgery for gynecologic disorders.
Gynecol Surg 9: 112-115, 2012

15.
Son YL, Ubuka T, Millar RP, Kanasaki H, Tsutsui K: Gonadotropin-inhibitory hormone inhibits GnRH-induced gonadotropin subunit gene transcriptions by inhibiting AC/cAMP/PKA-dependent ERK pathway in LβT2 cells.
Endocrinology 153: 2332-2343, 2012

16.
Kanasaki H, Aki Oride, Miyazaki K: Is it possible to predict the onset of side effects in patients treated with subcutaneous buserelin?.
Shimane J Med Sci 28:21-26, 2011

17.
Purwana IN, Kanasaki H, Oride A, Mijiddorj T Miyazaki K: Expression of the pituitary adenylate cyclase-activating polypeptide (PACAP) type 1 receptor (PAC1R) potentiates the effects of GnRH on gonadotropin subunit gene expression.
Biochem Biophys Res Commun 410: 295-300, 2011

18.
Kanasaki H, Aki Oride, Miyazaki K: Comparison of vaginal hysterectomy and tension-free vaginal mesh surgery for pelvic organ prolapsus: Review of the first 20 operations performed by a first-time surgeon.
Urogynaecologia Int Journal 25: 16-19, 2011

19.
Mijiddorj T, Kanasaki H, Purwana IN, Oride A and Miyazaki K: Stimulatory Effect of pituitary adenylate-cyclase activating polypeptide (PACAP) and its PACAP type I receptor (PAC1R) on prolactin synthesis in rat pituitary somatolactotroph GH3 Cells.
Mol Cell Endocrinol 339:172-179, 2011

20.
Kanasaki H, Purwana IN, Oride A, Mijiddorj T Miyazaki K: Possible Involvement of PACAP and PACAP type 1 receptor in GnRH-induced FSH β-subunit gene expression.
Regul Pept 167: 227-232, 2011

21.
Purwana IN, Kanasaki H, Oride A, Mijiddorj T Miyazaki K: Induction of Dual specificity phosphatase 1 (DUSP1) by pulsatile gonadotropin-releasing hormone stimulation and the role of gonadotropin subunit expression.
Biol Reprod 84: 996-1004, 2011

22.
Purwana IN, Kanasaki H, Oride A, Mijiddorj T, Shintani N, Hashimoto T, Baba A and Miyazaki K: GnRH-induced PACAP and PAC1 receptor expression in pituitary gonadotrophs: A possible role in the regulation of gonadotropin subunit gene expression.
Peptides 31:1748-1755, 2010

23.
Oride A, Kanasaki H, Purwana IN, Miyazaki K: Effects of metformin administration on plasma gonadotropin levels in women with infertility, with an in vitro study of the direct effects on the pituitary gonadotrophs.
Pituitary 13:236-241, 2010

24.
Purwana IN, Kanasaki H, Oride A, Miyazaki K: Induction of Dual Specificity Phosphatase 1 (DUSP1) by Gonadotropin-releasing hormone (GnRH) and the role for gonadotropin subunit gene expression in mouse pituitary gonadotroph LbetaT2 cells.
Biol Reprod 82: 352-362, 2010

25.
Kanasaki H, Mutiara S, Oride A, Purwana IN, Miyazaki K: Pulse frequency-dependent gonadotropin gene expression by adenylate cyclase-activation polypeptide 1 in perifused mouse pituitary LβT2 cells.
Biol Reprod 81: 465-472, 2009

26.
Oride A, Kanasaki H, Purwana IN, Miyazaki K: Follistatin, induced by Thyrotropin-releasing hormone (TRH), plays no role in prolactin expression but affects gonadotropin FSHβ expression as a paracrine factor in pituitary somatolactotroph GH3 cells.
Regul Pept 156: 65-71, 2009

27.
Oride A, Kanasaki H, Purwana IN, Miyazaki K: Possible Involvement of mitogen-activated protein kinase phosphatase-1 (MKP-1) in thyrotropin-releasing hormone (TRH)-induced prolactin gene expression.
Biochem Biophys Res Commun 382: 663-667, 2009

28.
Mutiara S, Kanasaki H, Oride A Shimasaki S, Yamamoto H, Miyazaki K: Follistatin gene expression by gonadotropin-releasing hormone: Role for cyclic AMP and mitogen-activated protein kinase signaling pathway in clonal gonadotroph LβT2 cells.
Mol Cell Endocrinol 307:125-132, 2009

29.
Oride A, Kanasaki H, Mutiara S, Purwana IN, Miyazaki K: Activation of extracellular signal-regulated kinase (ERK) and induction of mitogen-activated protein kinase phosphatase 1 (MKP1) by perifused thyrotropin-releasing hormone (TRH) stimulation in rat pituitary GH3 Cells.
Mol Cell Endocrinol 296:78-86, 2008

30.
Kanasaki H, Mutiara S, Oride A, Miyazaki K: Up-regulation of gonadotropin α-subunit gene by phosphatidylinositol 3-kinase inhibitors in clonal gonadotroph cells.
Neuro Endocrinol Lett 29: 529-535, 2008

31.
Mutiara S, Kanasaki H, Harada T, Oride A, Miyazaki K: The involvement of phosphatidylinositol 3-kinase in gonadotropin- releasing hormone induced gonadotropin α- and FSHβ subunit gene expression in clonal gonadotroph LβT2 cells.
Mol Cell Endocrinol 283: 1-11, 2008

32.
Harada T, Kanasaki H, Mutiara S, Oride A, Miyazaki K: Cyclic Adenosine 3',5'Monophosphate/Protein Kinase A and Mitogen-activated protein kinase 3/1 pathways are involved in adenylate cyclase-activating polypeptide 1-induced common alpha-glycoprotein subunit gene (Cga) expression in mouse pituitary gonadotroph LbetaT2 cells.
Biol Reprod 77:707-716, 2007

33.
Mutiara S, Kanasaki H, Harada T, Miyazaki K: Dopamine D2 receptor expression and regulation of gonadotropin α-subunit gene in clonal gonadotroph LβT2 cells.
Mol Cell Endocrinol 259: 22-29, 2006

34.
Ozaki T, Takahashi K, Kanasaki H, MiyazakinK: Expression and activation of mitogen-activated protein kinase in the human endometrium during the menstrual cycle.
Am J Obstet Gynecol 195:1340-1350, 2006

35.Kanasaki H, Bedecarrats GY, Kam KY, Xu S, Kaiser UB: GnRH pulse frequency-dependent activation of ERK pathways in perifused LβT2 cells.
Endocrinology 146: 5503-5513, 2005

36.Takahashi K, Ozaki T, Kanasaki H, Miyazaki K: Influence of ovarian cystectomy on the ovulatory function of the residual ovary.
Eur J Obstet Gynecol Reprod Biol 121:191-194, 2005

37.Ozaki T, Takahashi K, Kanasaki H, Iida K, Miyazaki K: Expression of type I interferon receptor and interferon-induced Mx protein in human endometrium during the menstrual cycle.
Fertil Steril 83: 163-170, 2005

38.Pask AJ, Kanasaki H, Kaiser UB, Conn PM, Janovick JA, Stockton DW, Hess DL, Justice MJ, Behringer RR: A novel mouse model of hypogonadotrophic hypogonadism: ENU-induced gonadotrophin releasing hormone receptor gene mutation.
Mol Endocrinol 19: 972-981, 2005

39.Kanasaki H*, Meysing AU*, Bedecarrats GY, Acierno JS Jr, Conn PM, Martin KA, Seminara SB, Hall JE, Crowley WF Jr, Kaiser UB.(* Equally contributed): GnRHR mutations in a woman with idiopathic hypogonadotropic hypogonadism, Highlight the differential sensitivity of luteinizing hormone and follicle-stimulating hormone to gonadotropin-releasing hormone.
J Clin Endocrinol Metab 89:3189-3198,2004

40.Takahashi K, Karino K, Kanasaki K, Miyazaki K: Altered kinetics of pituitary response to gonadotropin-releasing hormone in women with variant luteinizing hormone: Correlation with ovulatory disorders.
Horm Res 61: 27-32, 2004

41.Yamada Y, Yamamoto H, Yonehara T, Kanasaki H, Nakanishi H, Miyamoto E, Miyazaki K: Differential activation of the luteinizing hormone beta-subunit promoter by activin and gonadotropin-releasing hormone: a role for the mitogen-activated protein kinase signaling pathway in LβT2 gonadotrophs.
Biol Reprod 70: 236-243, 2004

42.Fujiwaki R, Iida K, Nakayama K, Kanasaki H, Ozaki T, Hata K, Sakai E, Miyazaki K: Dihydropyrimidine dehydrogenase in normal and malignant endometrium: relationship with cell proliferation and thymidine phosphorylase.
Virchows Arch 443:672-677, 2003

43.Hata K, Osaki M, Kanasaki H, Nakayama K, Fujiwaki R, Ito H, Miyazaki K:Induction of thymidine phosphorylase expression and enhancement of Furtulon sensitivity by taxol in a human ovarian carcinoma cell line.
Anticancer Res 23:2665-2669,2003

44.Yonehara Y, Yamada Y, Kanasaki H, Yamamoto H, Fukunaga K, Miyazaki K, Miyamoto E: Characterization of αT3-1 Cells Stably Transfected with luteininzing hormone β-subunit complementary deoxyribonucleic acid.
Endocr J 50: 341- 354, 2003

45.Hata K, Dhar DK, Kanasaki H, Nakayama K, Fujiwaki R, Katabuchi H, Okamura H, Nagasue N, Miyazaki K: Serum endostatin levels in patients with epithelial ovarian cancer.
Anticancer Res 23:1907-1912, 2003

46.Hata K, Osaki M, Kanasaki H, Nakayama K, Fujiwaki R, Ito H, Miyazaki K: Induction of thymidine phosphorylase expression by taxol does not enhance Furtulon sensitivity in a cisplatin-resistant human ovarian carcinoma cell line.
Anticancer Res 23:1525-1531, 2003

47.Takahashi K, Karino K, Kanasaki H, Kurioka H, Ozaki T, Yonehara T, Miyazaki K: Influence of missense mutation and silent mutation of LH beta-subunit gene in Japanese patients with ovulatory disorders.
Eur J Hum Genet 11:402-408, 2003

48.Fujiwaki R, Iida K, Nakayama K, Kanasaki H, Hata K, Katabuchi H, Okamura H, Miyazaki K: Clinical significance of interleukin-1 receptor antagonist in patients with cervical carcinoma.
Gynecol Oncol 89: 77-83, 2003

49.Kanasaki H, Yonehara T, Yamada Y, Takahashi K, Hata K, Fujiwaki R, Yamamoto H, Takeuchi Y, Fukunaga K, Miyamoto E, Miyazaki K: Regulation of gonadotropin α-subunit gene expression by dopamine D2 receptor agonist in clonal gonadotroph αT3-1 cells.
Biol Reprod 67: 1218-1224, 2002

50.Fujiwaki R, Iida K, Kanasaki H, Ozaki T, Hata K, Miyazaki K: Cyclooxygenase-2 expression in endometrial cancer: Correlation with microvessel count and expression of VEGF and thymidine phosphorylase.
Hum Pathol 33 :213-219; 2002

51.Ozaki T, Takahashi K, Kanasaki H, Miyazaki K: Evaluation of acrosome reaction and viability of human sperm with two fluorescent dyes.
Arch Gynecol Obstet 266: 114-117, 2002

52.Kanasaki H, Yonehara T, Yamamoto H, Takeuchi Y, Fukunaga K, Takahashi K, Miyazaki K, Miyamoto E: Differential regulation of pituitary hormone secretion and gene expression by thyrotropin-releasing hormone. A role of mitogen-activated protein kinase signaling cascade in rat pituitary GH3 cells.
Biol Reprod 67: 107-113, 2002

53.Takahashi K, Kurioka H, Irikoma M, Ozaki T, Kanasaki H, Miyazaki K: Benign or malignant ovarian neoplasms and ovarian endometriomas.
J Am Assoc Gynecol Laparosc 8:278-284, 2001

54.Yonehara T, Kanasaki H, Yamamoto H, Fukunaga K, Miyazaki K, Miyamoto E: Involvement of mitogen-activated protein kinase in cAMP-induced prolactin gene expression in GH3 cells.
Endocrinology 142 : 2811-2819, 2001

55.Takahashi K, Kurioka H, Ozaki T, Kanasaki H, Miyazaki K, Karino K: Pituitary response to luteinizing hormone-releasing hormone in women with variant luteinizing hormone.
Euro J Endocrinol 143: 375-381, 2000

56.Munir I, Fukunaga K, Kanasaki H, Miyazaki K, Ohba T, Okamura H, Miyamoto E: Expression of cyclo-oxygenase 2 by prostaglandin E2 in human endometrial adenocarcinoma cell line HEC-1B.
Biol Reprod 63: 933-941, 2000

57.Kanasaki H, Fukunaga K, Takahashi K, Miyazaki K, Miyamoto E: Involvement of p38 mitogen-activated protein kinase activation in bromocriptine-induced apoptosis in rat pituitary GH3 cells.
Biol Reprod 62: 1486-1494, 2000

58.Takahashi K, Okada M, Ozaki T, Kurioka H, Manabe A, Kanasaki H, Miyazaki K: Safety and efficacy of oestriol for symptoms of natural or surgically induced menopause.
Human Reprod 15: 1028-1036, 2000

59.Takahashi K, Manabe A, Okada M, Kurioka H, Kanasaki H, Miyazaki K: Efficacy and safety of oral estriol for managing postmenopausal symptoms.
Maturitas 34: 169-177, 1999

60.Takahashi K, Karino K, Kurioka H, Ozaki T, Kanasaki H, Kohsaka M, Miyazaki M: Estradiol-17β measurement in women receiving conjugated estrogens. Dissociation between two commercial methods.
Clin Chim Acta 284: 69-79, 1999

61.Kanasaki H, Fukunaga K, Takahashi K, Miyazaki K, Miyamoto E: Mitogen-activated protein kinase activation by stimulation with thyrotropin-releasing hormone in rat pituitary GH3 cells.
Biol Reprod 61: 319-325, 1999

62.Takahashi K, Ozaki T, Okada M, Kurioka H, Kanasaki H, Miyazaki K: Increased prevalence of luteinizing hormone β-subunit variant in patients with premature ovarian failure.
Fertil Steril 71: 96-101, 1999

63.Takahashi K, Kurioka H, Ozaki T, Kanasaki H, Kohsaka M, Miyazaki K, Karino K: Increased prevalence of luteinizing hormone β-subunit variant in Japanese infertility patients.
Human Reprod 13: 3338-3344, 1998



症例報告

1.
Oride A, Kanasaki H, Miyazaki K: Disappearance of a uterine arteriovenous malformation following long-term administration of oral norgestrel/ethinyl estradiol.
J Obstet Gynaecol Res: in press, 2014

2.
Purwana IN, Kanasaki H, Oride A and Miyazaki K:Successful pregnancy after the treatment of primary amenorrhea in a patient with non-classical congenital adrenal hyperplasia: a case report.
J Obstet Gynaecol Res 39: 406-409, 2013

3.
Kanasaki H, Oride A, Mijiddorj T, Purwana IN and Kohji Miyazaki: Secondary amenorrhea in a patient with spinocerebellar degeneration treated with thyrotropin-releasing hormone (TRH): a case report and in vitro analysis.
J Med Case Rep 5: 567, 2011

4.
Takahashi K, Ozaki T, Kanasaki H, Miyazaki K: Successful pregnancy in a woman with ovarian failure associated with mutation in the β-subunit of luteinizing hormone.
Horm Res 55: 258-263, 2001

5.
Takahashi K, Kurioka H, Kanasaki K, Okada M, Ozaki T, Miyazaki K: A case of a pregnant woman with luteal insufficiency and a mutation in the β-subunit of luteinizing hormone.
Int J Fertil Womens Med 45: 327-334. 2000

6.
Kanasaki H, Senoh D, Hata K, Hata T: Transvaginal color doppler demonstration of fetal coronary blood flow in a case of fetal hydrops with cystic hygroma in the 17 th week of gestation.
J Med Ultrasonics 24: 901-903, 1997



欧文総説

1.
Kanasaki H, Purwana IN, Miyazaki K: Possible role of PACAP and its PAC1 receptor in the differential regulation of pituitary LHβ- and FSHβ- subunit gene expression by pulsatile GnRH stimulation.
Biol Reprod 88: 1-5, 2013

2.
Kanasaki H, Purwana IN, Oride A, Mijiddorj T Miyazaki K: Extracellular signal-regulated kinase activation and mitogen-activated protein kinase phosphatase 1 induction by pulsatile gonadotropin-releasing hormone in pituitary gonadotrophs.
J Signal Transduct 2012: 1-7, 2012

3.
Kanasaki H, Oride A, Miyazaki K: Paracrine control of gonadotrophs by somatolactotrophs through TRH-induced follistatin production.
The Open Neuroendocrinology Journal 4: 102-110, 2011